null

SMILES: Oc1[nH]c(=O)sc1Cc1ccc(OCCN2CCS(=O)(=O)CC2)cc1

InChI Key: InChIKey=RMACIPXDLYBHGN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 118082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human))	BDBM118082 (US8637558, 119 | US8637558, 126) Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCCN2CCS(=O)(=O)CC2)cc1 Show InChI InChI=1S/C16H22N2O5S2/c19-15-14(24-16(20)17-15)11-12-1-3-13(4-2-12)23-8-5-18-6-9-25(21,22)10-7-18/h1-4,9,19,21-22,25H,5-8,10-11H2,(H,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.21E+3	n/a	n/a	n/a	n/a	7.5	n/a
Industry-Academic Cooperation Foundation, Chosun University US Patent					Assay Description Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...				US Patent US8637558 (2014) BindingDB Entry DOI: 10.7270/Q280519F
					More data for this Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human))	BDBM118082 (US8637558, 119 | US8637558, 126) Show SMILES Oc1[nH]c(=O)sc1Cc1ccc(OCCN2CCS(=O)(=O)CC2)cc1 Show InChI InChI=1S/C16H22N2O5S2/c19-15-14(24-16(20)17-15)11-12-1-3-13(4-2-12)23-8-5-18-6-9-25(21,22)10-7-18/h1-4,9,19,21-22,25H,5-8,10-11H2,(H,17,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.39E+3	n/a	n/a	n/a	n/a	7.5	n/a
Industry-Academic Cooperation Foundation, Chosun University US Patent					Assay Description Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...				US Patent US8637558 (2014) BindingDB Entry DOI: 10.7270/Q280519F
					More data for this Ligand-Target Pair