BDBM118332 US8653111, 43

SMILES: Cc1cn(nn1)-c1c[nH]n(-c2cnccn2)c1=O

InChI Key: InChIKey=QLTPICLDLHXRRJ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 118332   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl hydroxylase EGLN2 (Homo sapiens (Human))	BDBM118332 (US8653111, 43) Show SMILES Cc1cn(nn1)-c1c[nH]n(-c2cnccn2)c1=O Show InChI InChI=1S/C10H9N7O/c1-7-6-16(15-14-7)8-4-13-17(10(8)18)9-5-11-2-3-12-9/h2-6,13H,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...				US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD
					More data for this Ligand-Target Pair