BDBM118345 US8653111, 113

SMILES: O=c1c(c[nH]n1-c1cc(ncn1)N1CCSCC1)-n1ccnn1

InChI Key: InChIKey=RNUYQJMMQZQPJZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 118345   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 2 (Homo sapiens (Human))	BDBM118345 (US8653111, 113) Show SMILES O=c1c(c[nH]n1-c1cc(ncn1)N1CCSCC1)-n1ccnn1 Show InChI InChI=1S/C13H14N8OS/c22-13-10(20-2-1-16-18-20)8-17-21(13)12-7-11(14-9-15-12)19-3-5-23-6-4-19/h1-2,7-9,17H,3-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Bayer Intellectual Property GmbH US Patent					Assay Description Hydroxylated HIF bonds specifically to the von Hippel-Lindau protein-elongin B-elongin C complex (VBC complex). This interaction occurs only if HIF i...				US Patent US8653111 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GMD
					More data for this Ligand-Target Pair