BDBM119045 US8674100, 64
SMILES: CC(C)(N1CCN(CC(=O)O[Na])CC1)c1ccc(NC(=O)c2ncc([nH]2)C#N)c(c1)C1=CCC(C)(C)CC1
InChI Key: InChIKey=PGXUTDVXKBXNAZ-UHFFFAOYSA-M
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Macrophage colony-stimulating factor 1 receptor (c-Fms) (Mus musculus (Mouse)) | BDBM119045 (US8674100, 64) | PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.930 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Janssen Pharmaceutica, N.V. US Patent | Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-... | US Patent US8674100 (2014) BindingDB Entry DOI: 10.7270/Q23777CF | |||||||||||
More data for this Ligand-Target Pair |