BDBM119064 US8674100, 151

SMILES: CC1(C)CCC(=CC1)c1cc(CN2CCNCC2)ccc1NC(=O)c1ncc([nH]1)C#N

InChI Key: InChIKey=FCEGNRXMBLQREV-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 119064   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Macrophage colony-stimulating factor 1 receptor (c-Fms) (Mus musculus (Mouse))	BDBM119064 (US8674100, 151) Show SMILES CC1(C)CCC(=CC1)c1cc(CN2CCNCC2)ccc1NC(=O)c1ncc([nH]1)C#N |c:5| Show InChI InChI=1S/C24H30N6O/c1-24(2)7-5-18(6-8-24)20-13-17(16-30-11-9-26-10-12-30)3-4-21(20)29-23(31)22-27-15-19(14-25)28-22/h3-5,13,15,26H,6-12,16H2,1-2H3,(H,27,28)(H,29,31)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.820	n/a	n/a	n/a	n/a	7.5	n/a
Janssen Pharmaceutica, N.V. US Patent					Assay Description A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...				US Patent US8674100 (2014) BindingDB Entry DOI: 10.7270/Q23777CF
					More data for this Ligand-Target Pair