BDBM119117 MurF inhibitor (compound 59)

SMILES: OCCc1ccccc1Nc1nc(Cl)nc(Cl)n1

InChI Key: InChIKey=LMPQRYXIMQDJIS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119117   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
DNA topoisomerase 2-alpha (Homo sapiens (Human))	BDBM119117 (MurF inhibitor (compound 59)) Show SMILES OCCc1ccccc1Nc1nc(Cl)nc(Cl)n1 Show InChI InChI=1S/C11H10Cl2N4O/c12-9-15-10(13)17-11(16-9)14-8-4-2-1-3-7(8)5-6-18/h1-4,18H,5-6H2,(H,14,15,16,17)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
National Institute of Chemistry Curated by ChEMBL					Assay Description Inhibition of human DNA topoisomerase IIalpha using plasmid pNO1 as a substrate after 30 mins				Bioorg Med Chem 23: 4218-29 (2015) BindingDB Entry DOI: 10.7270/Q2RJ4M72
					More data for this Ligand-Target Pair
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase (Escherichia coli)	BDBM119117 (MurF inhibitor (compound 59)) Show SMILES OCCc1ccccc1Nc1nc(Cl)nc(Cl)n1 Show InChI InChI=1S/C11H10Cl2N4O/c12-9-15-10(13)17-11(16-9)14-8-4-2-1-3-7(8)5-6-18/h1-4,18H,5-6H2,(H,14,15,16,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Ljubljana, A?kerceva 7, 1000 Ljubljana, Slovenia									Bioorg Chem 55: 2-15 (2014) Article DOI: 10.1016/j.bioorg.2014.03.008 BindingDB Entry DOI: 10.7270/Q2ZG6QWR
					More data for this Ligand-Target Pair