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SMILES: COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1ccsc1

InChI Key: InChIKey=ZYUCYEGMBITLJA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 119457   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin E2 receptor EP1 subtype


(Rattus norvegicus (Rat))		BDBM119457
PNG
(US8680120, 9-25)
Show SMILES COc1ccc2n(Cc3cccc(c3)C(O)=O)c(cc2c1)-c1ccsc1
Show InChI InChI=1S/C21H17NO3S/c1-25-18-5-6-19-17(10-18)11-20(16-7-8-26-13-16)22(19)12-14-3-2-4-15(9-14)21(23)24/h2-11,13H,12H2,1H3,(H,23,24)
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Similars
US Patent
n/an/a 35n/an/an/an/an/an/a



Kissei Pharmaceutical Co., Ltd.

US Patent


Assay Description
The rat EP1 receptor-expressing cells were washed with the assay buffer. 100 μL of a fluorescent calcium indicator (Fluo-4 NW Calcium Assay Kit ...

US Patent US8680120 (2014)


BindingDB Entry DOI: 10.7270/Q2183554
More data for this
Ligand-Target Pair