BDBM119485 US8680275, 9

SMILES: O=C(N1CCC2CN(C2C1)c1nccc(n1)-c1ccccc1)c1ccccc1-c1ccccc1

InChI Key: InChIKey=ZYWRJPNACZTMSM-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119485   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 1 (Homo sapiens (Human))	BDBM119485 (US8680275, 9) Show SMILES O=C(N1CCC2CN(C2C1)c1nccc(n1)-c1ccccc1)c1ccccc1-c1ccccc1 Show InChI InChI=1S/C29H26N4O/c34-28(25-14-8-7-13-24(25)21-9-3-1-4-10-21)32-18-16-23-19-33(27(23)20-32)29-30-17-15-26(31-29)22-11-5-2-6-12-22/h1-15,17,23,27H,16,18-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	22	-9.70	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description Chinese ovary cells (CHO) stably expressing human orexin 1 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco...				US Patent US8680275 (2014) BindingDB Entry DOI: 10.7270/Q2WH2NPF
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM119485 (US8680275, 9) Show SMILES O=C(N1CCC2CN(C2C1)c1nccc(n1)-c1ccccc1)c1ccccc1-c1ccccc1 Show InChI InChI=1S/C29H26N4O/c34-28(25-14-8-7-13-24(25)21-9-3-1-4-10-21)32-18-16-23-19-33(27(23)20-32)29-30-17-15-26(31-29)22-11-5-2-6-12-22/h1-15,17,23,27H,16,18-20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	33	-9.48	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				US Patent US8680275 (2014) BindingDB Entry DOI: 10.7270/Q2WH2NPF
					More data for this Ligand-Target Pair