BDBM119502 US8680275, 57

SMILES: Cc1cc(C)nc(n1)N1CC2CN(CC12)C(=O)c1ccccc1-c1cccs1

InChI Key: InChIKey=GBJJYXHANNSQKY-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119502   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM119502 (US8680275, 57) Show SMILES Cc1cc(C)nc(n1)N1CC2CN(CC12)C(=O)c1ccccc1-c1cccs1 Show InChI InChI=1S/C22H22N4OS/c1-14-10-15(2)24-22(23-14)26-12-16-11-25(13-19(16)26)21(27)18-7-4-3-6-17(18)20-8-5-9-28-20/h3-10,16,19H,11-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	29	-9.55	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				US Patent US8680275 (2014) BindingDB Entry DOI: 10.7270/Q2WH2NPF
					More data for this Ligand-Target Pair
Orexin receptor type 1 (Homo sapiens (Human))	BDBM119502 (US8680275, 57) Show SMILES Cc1cc(C)nc(n1)N1CC2CN(CC12)C(=O)c1ccccc1-c1cccs1 Show InChI InChI=1S/C22H22N4OS/c1-14-10-15(2)24-22(23-14)26-12-16-11-25(13-19(16)26)21(27)18-7-4-3-6-17(18)20-8-5-9-28-20/h3-10,16,19H,11-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.57E+3	-6.90	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description Chinese ovary cells (CHO) stably expressing human orexin 1 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco...				US Patent US8680275 (2014) BindingDB Entry DOI: 10.7270/Q2WH2NPF
					More data for this Ligand-Target Pair