BDBM119560 US8680275, 116

SMILES: Fc1cccc(C(=O)N2CC[C@H]3CN([C@H]3C2)c2cnc3ccccc3n2)c1-n1nccn1

InChI Key: InChIKey=FLOMBNYPQJLSQF-YWZLYKJASA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119560   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 1 (Homo sapiens (Human))	BDBM119560 (US8680275, 116) Show SMILES Fc1cccc(C(=O)N2CC[C@H]3CN([C@H]3C2)c2cnc3ccccc3n2)c1-n1nccn1 |r| Show InChI InChI=1S/C23H20FN7O/c24-17-5-3-4-16(22(17)31-26-9-10-27-31)23(32)29-11-8-15-13-30(20(15)14-29)21-12-25-18-6-1-2-7-19(18)28-21/h1-7,9-10,12,15,20H,8,11,13-14H2/t15-,20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	23	-9.68	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description Chinese ovary cells (CHO) stably expressing human orexin 1 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco...				US Patent US8680275 (2014) BindingDB Entry DOI: 10.7270/Q2WH2NPF
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM119560 (US8680275, 116) Show SMILES Fc1cccc(C(=O)N2CC[C@H]3CN([C@H]3C2)c2cnc3ccccc3n2)c1-n1nccn1 |r| Show InChI InChI=1S/C23H20FN7O/c24-17-5-3-4-16(22(17)31-26-9-10-27-31)23(32)29-11-8-15-13-30(20(15)14-29)21-12-25-18-6-1-2-7-19(18)28-21/h1-7,9-10,12,15,20H,8,11,13-14H2/t15-,20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	28	-9.57	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				US Patent US8680275 (2014) BindingDB Entry DOI: 10.7270/Q2WH2NPF
					More data for this Ligand-Target Pair