BDBM119642 US8680275, 2

SMILES: Cc1cc(C)nc(n1)N1CC2CCN(CC12)C(=O)c1ccccc1-c1ccco1

InChI Key: InChIKey=WNWUDGHZOXYLNZ-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119642   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 2 (Homo sapiens (Human))	BDBM119642 (US8680275, 2) Show SMILES Cc1cc(C)nc(n1)N1CC2CCN(CC12)C(=O)c1ccccc1-c1ccco1 Show InChI InChI=1S/C23H24N4O2/c1-15-12-16(2)25-23(24-15)27-13-17-9-10-26(14-20(17)27)22(28)19-7-4-3-6-18(19)21-8-5-11-29-21/h3-8,11-12,17,20H,9-10,13-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	4	-10.6	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				US Patent US8680275 (2014) BindingDB Entry DOI: 10.7270/Q2WH2NPF
					More data for this Ligand-Target Pair
Orexin receptor type 1 (Homo sapiens (Human))	BDBM119642 (US8680275, 2) Show SMILES Cc1cc(C)nc(n1)N1CC2CCN(CC12)C(=O)c1ccccc1-c1ccco1 Show InChI InChI=1S/C23H24N4O2/c1-15-12-16(2)25-23(24-15)27-13-17-9-10-26(14-20(17)27)22(28)19-7-4-3-6-18(19)21-8-5-11-29-21/h3-8,11-12,17,20H,9-10,13-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	61	-9.14	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description Chinese ovary cells (CHO) stably expressing human orexin 1 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco...				US Patent US8680275 (2014) BindingDB Entry DOI: 10.7270/Q2WH2NPF
					More data for this Ligand-Target Pair