BDBM119647 US8680275, 10

SMILES: Cc1ccc(cc1)-c1ccccc1C(=O)N1CCC2CN(C2C1)c1cnc2ccccc2n1

InChI Key: InChIKey=WBLFAGDVIJVAMF-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 119647   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin receptor type 1 (Homo sapiens (Human))	BDBM119647 (US8680275, 10) Show SMILES Cc1ccc(cc1)-c1ccccc1C(=O)N1CCC2CN(C2C1)c1cnc2ccccc2n1 Show InChI InChI=1S/C28H26N4O/c1-19-10-12-20(13-11-19)22-6-2-3-7-23(22)28(33)31-15-14-21-17-32(26(21)18-31)27-16-29-24-8-4-5-9-25(24)30-27/h2-13,16,21,26H,14-15,17-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	18	-9.81	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description Chinese ovary cells (CHO) stably expressing human orexin 1 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco...				US Patent US8680275 (2014) BindingDB Entry DOI: 10.7270/Q2WH2NPF
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM119647 (US8680275, 10) Show SMILES Cc1ccc(cc1)-c1ccccc1C(=O)N1CCC2CN(C2C1)c1cnc2ccccc2n1 Show InChI InChI=1S/C28H26N4O/c1-19-10-12-20(13-11-19)22-6-2-3-7-23(22)28(33)31-15-14-21-17-32(26(21)18-31)27-16-29-24-8-4-5-9-25(24)30-27/h2-13,16,21,26H,14-15,17-18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	44	-9.32	n/a	n/a	n/a	n/a	n/a	n/a	4
Janssen Pharmaceutica NV US Patent					Assay Description HEK293 stably expressing human orexin-2 receptor (Genebank accession number NM 001526) were grown to confluency in DMEM/F12 (Gibco, Cat #11039), in D...				US Patent US8680275 (2014) BindingDB Entry DOI: 10.7270/Q2WH2NPF
					More data for this Ligand-Target Pair