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SMILES: CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(CNC(=O)c4cccc(c4)-c4cn[nH]c4)c3)sc2C1

InChI Key: InChIKey=OIBJPIDSCRFVOF-QFIPXVFZSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 119967   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Rho-associated protein kinase 2


(Homo sapiens (Human))		BDBM119967
PNG
(US8697911, 132)
Show SMILES CN(C)[C@H]1CCc2nc(NC(=O)c3cccc(CNC(=O)c4cccc(c4)-c4cn[nH]c4)c3)sc2C1 |r|
Show InChI InChI=1S/C27H28N6O2S/c1-33(2)22-9-10-23-24(13-22)36-27(31-23)32-26(35)19-7-3-5-17(11-19)14-28-25(34)20-8-4-6-18(12-20)21-15-29-30-16-21/h3-8,11-12,15-16,22H,9-10,13-14H2,1-2H3,(H,28,34)(H,29,30)(H,31,32,35)/t22-/m0/s1
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KEGG

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antibodypedia
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PC cid
PC sid
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Similars
US Patent
n/an/a 0.320n/an/an/an/a7.2n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
This assay is performed using FAM S6 substrate peptide (Catalogue #R7184) and IMAP FP Screening Express Kit detection reagents from Molecular Devices...

US Patent US8697911 (2014)


BindingDB Entry DOI: 10.7270/Q25X27KR
More data for this
Ligand-Target Pair