BDBM120147 US8697696, 4

SMILES: Cc1nnn(c1COc1cc(C(=O)NN2CCOCC2)n(C)n1)-c1ccc(F)cc1

InChI Key: InChIKey=JRNUSJIXULHHSP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120147   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gamma-aminobutyric acid receptor subunit alpha-5 (Homo sapiens (Human))	BDBM120147 (US8697696, 4) Show SMILES Cc1nnn(c1COc1cc(C(=O)NN2CCOCC2)n(C)n1)-c1ccc(F)cc1 Show InChI InChI=1S/C19H22FN7O3/c1-13-17(27(24-21-13)15-5-3-14(20)4-6-15)12-30-18-11-16(25(2)22-18)19(28)23-26-7-9-29-10-8-26/h3-6,11H,7-10,12H2,1-2H3,(H,23,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	22.2	-9.70	n/a	n/a	n/a	n/a	n/a	7.5	4
Roche Palo Alto LLC US Patent					Assay Description Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell membranes, [3H]flumazenil at a conc...				US Patent US8697696 (2014) BindingDB Entry DOI: 10.7270/Q2DB80HJ
					More data for this Ligand-Target Pair