BDBM120327 US8703811, 69

SMILES: CCNC(=O)c1ccc(s1)-n1c(CC)nc2cc(F)ccc12

InChI Key: InChIKey=RXKWQXKTCVMIHA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120327   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dihydroorotate dehydrogenase (quinone), mitochondrial (Plasmodium falciparum)	BDBM120327 (US8703811, 69) Show SMILES CCNC(=O)c1ccc(s1)-n1c(CC)nc2cc(F)ccc12 Show InChI InChI=1S/C16H16FN3OS/c1-3-14-19-11-9-10(17)5-6-12(11)20(14)15-8-7-13(22-15)16(21)18-4-2/h5-9H,3-4H2,1-2H3,(H,18,21)	PDB MMDB KEGG UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	178	n/a	n/a	n/a	n/a	n/a	n/a
Genzyme Corporation; Massachusetts Institute of Technology; President and Fellows of Harvard College US Patent					Assay Description Type 2 DHODH activity was monitored with either the direct assay measuring the formation of orotate or via a chromogen reduction assay using DCIP. Al...				US Patent US8703811 (2014) BindingDB Entry DOI: 10.7270/Q2WD3Z7P
					More data for this Ligand-Target Pair