BDBM120761 US8703761, 12-3

SMILES: CC(C)(NC(=O)C1(C)CC1)C(=O)Nc1nc(c(s1)C(=O)c1ccc(F)cc1)C(F)(F)F

InChI Key: InChIKey=RBNFMENBOMXIOK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120761   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
acyl coA-diacylglycerol acyl transferase 1 (DGAT1) (Homo sapiens (Human))	BDBM120761 (US8703761, 12-3) Show SMILES CC(C)(NC(=O)C1(C)CC1)C(=O)Nc1nc(c(s1)C(=O)c1ccc(F)cc1)C(F)(F)F Show InChI InChI=1S/C20H19F4N3O3S/c1-18(2,27-16(30)19(3)8-9-19)15(29)26-17-25-14(20(22,23)24)13(31-17)12(28)10-4-6-11(21)7-5-10/h4-7H,8-9H2,1-3H3,(H,27,30)(H,25,26,29)	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.18E+3	n/a	n/a	n/a	n/a	7.5	4
Novartis AG US Patent					Assay Description The enzyme preparation used in this assay is a membrane preparation from Sf9 cells overexpressing human (His)6DGAT1. During all steps samples were ch...				US Patent US8703761 (2014) BindingDB Entry DOI: 10.7270/Q2057DM1
					More data for this Ligand-Target Pair