| Reaction Details |
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 | Report a problem with these data |
| Target | Diacylglycerol O-acyltransferase 1 [89-488] |
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| Ligand | BDBM120761 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| pH | 7.5±n/a |
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| Temperature | 277.15±n/a K |
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| IC50 | 1180±n/a nM |
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| Comments | extracted |
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| Citation |  Forster, CJ; Kwak, Y; Nakajima, K; Wang, B Organic compounds US Patent US8703761 Publication Date 4/22/2014 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Diacylglycerol O-acyltransferase 1 [89-488] |
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| Name: | Diacylglycerol O-acyltransferase 1 [89-488] |
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| Synonyms: | AGRP1 | DGAT | DGAT1 | DGAT1_HUMAN | acyl coA-diacylglycerol acyl transferase 1 (DGAT1) |
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| Type: | Protein |
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| Mol. Mass.: | 46366.89 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O75907[89-488] |
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| Residue: | 400 |
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| Sequence: | LNWCVVMLILSNARLFLENLIKYGILVDPIQVVSLFLKDPYSWPAPCLVIAANVFAVAAF
QVEKRLAVGALTEQAGLLLHVANLATILCFPAAVVLLVESITPVGSLLALMAHTILFLKL
FSYRDVNSWCRRARAKAASAGKKASSAAAPHTVSYPDNLTYRDLYYFLFAPTLCYELNFP
RSPRIRKRFLLRRILEMLFFTQLQVGLIQQWMVPTIQNSMKPFKDMDYSRIIERLLKLAV
PNHLIWLIFFYWLFHSCLNAVAELMQFGDREFYRDWWNSESVTYFWQNWNIPVHKWCIRH
FYKPMLRRGSSKWMARTGVFLASAFFHEYLVSVPLRMFRLWAFTGMMAQIPLAWFVGRFF
QGNYGNAAVWLSLIIGQPIAVLMYVHDYYVLNYEAPAAEA
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| BDBM120761 |
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| n/a |
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| Name | BDBM120761 |
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| Synonyms: | US8703761, 12-3 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H19F4N3O3S |
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| Mol. Mass. | 457.442 |
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| SMILES | CC(C)(NC(=O)C1(C)CC1)C(=O)Nc1nc(c(s1)C(=O)c1ccc(F)cc1)C(F)(F)F |
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| Structure | 
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