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SMILES: Nc1ccc(CC(C(O)=O)c2cn(CC3CCCCN3C(=O)c3ccccc3)cn2)cn1

InChI Key: InChIKey=DXPCOTQKAXKFMI-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120788   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Carboxypeptidase B


(Homo sapiens (Human))		BDBM120788
PNG
(US8710232, 15)
Show SMILES Nc1ccc(CC(C(O)=O)c2cn(CC3CCCCN3C(=O)c3ccccc3)cn2)cn1
Show InChI InChI=1S/C24H27N5O3/c25-22-10-9-17(13-26-22)12-20(24(31)32)21-15-28(16-27-21)14-19-8-4-5-11-29(19)23(30)18-6-2-1-3-7-18/h1-3,6-7,9-10,13,15-16,19-20H,4-5,8,11-12,14H2,(H2,25,26)(H,31,32)
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US Patent
n/an/a 12n/an/an/an/a7.425



Sanofi-Aventis Deutschland GmbH

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ...

US Patent US8710232 (2014)


BindingDB Entry DOI: 10.7270/Q2KW5DQ4
More data for this
Ligand-Target Pair