BDBM120792 US8710232, 25
SMILES: Nc1ccc(CC(C(O)=O)c2cn(Cc3ccc(OC(F)(F)F)cc3)cn2)cn1
InChI Key: InChIKey=HGQDIZXJKHDJMJ-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thrombin-activatable fibrinolysis (TAFI) (Homo sapiens (Human)) | BDBM120792 (US8710232, 25) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 1.05E+4 | n/a | n/a | n/a | n/a | 7.4 | 25 |
Sanofi-Aventis Deutschland GmbH US Patent | Assay Description The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI activity kit from American Diagnostica (Pr. No. 874). This ... | US Patent US8710232 (2014) BindingDB Entry DOI: 10.7270/Q2KW5DQ4 | |||||||||||
More data for this Ligand-Target Pair |