BDBM120810 US8716482, 13

SMILES: CS(=O)(=O)n1cc2CN(Cc2n1)[C@@H]1C[C@H](N)C(N(Cc2cncnc2)C1)c1cc(F)ccc1F

InChI Key: InChIKey=NUBQQPLNVAYNFW-QIFHVCNWSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120810   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM120810 (US8716482, 13) Show SMILES CS(=O)(=O)n1cc2CN(Cc2n1)[C@@H]1C[C@H](N)C(N(Cc2cncnc2)C1)c1cc(F)ccc1F |r| Show InChI InChI=1S/C22H25F2N7O2S/c1-34(32,33)31-10-15-9-29(12-21(15)28-31)17-5-20(25)22(18-4-16(23)2-3-19(18)24)30(11-17)8-14-6-26-13-27-7-14/h2-4,6-7,10,13,17,20,22H,5,8-9,11-12,25H2,1H3/t17-,20+,22?/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	3	n/a	n/a	n/a	n/a	7.5	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...				US Patent US8716482 (2014) BindingDB Entry DOI: 10.7270/Q2G73CC0
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