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SMILES: COc1ccccc1-c1cc(ncn1)N(C)C(=O)[C@@H]1CCCNC1

InChI Key: InChIKey=LLVLXDYXPDNWEX-CYBMUJFWSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 120933   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Cyclin-dependent kinase 9


(Homo sapiens (Human))		BDBM120933
PNG
(US8716296, 1)
Show SMILES COc1ccccc1-c1cc(ncn1)N(C)C(=O)[C@@H]1CCCNC1 |r|
Show InChI InChI=1S/C18H22N4O2/c1-22(18(23)13-6-5-9-19-11-13)17-10-15(20-12-21-17)14-7-3-4-8-16(14)24-2/h3-4,7-8,10,12-13,19H,5-6,9,11H2,1-2H3/t13-/m1/s1
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Similars
US Patent
n/an/a 10n/an/an/an/a7.5n/a



Ingenium Pharmaceuticals GmbH

US Patent


Assay Description
All kinase assays were performed in 96-well FlashPlates from Perkin Elmer/NEN (Boston, Mass., USA) in a 50 μl reaction volume. The reaction mixt...

US Patent US8716296 (2014)


BindingDB Entry DOI: 10.7270/Q2PN949G
More data for this
Ligand-Target Pair