BDBM121408 US8722709, 11

SMILES: CC(C)n1nccc1-c1ccnc(NC(N)=O)c1

InChI Key: InChIKey=DWGWUIMZPWHNNB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 121408   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mineralocorticoid receptor (Homo sapiens (Human))	BDBM121408 (US8722709, 11) Show SMILES CC(C)n1nccc1-c1ccnc(NC(N)=O)c1 Show InChI InChI=1S/C12H15N5O/c1-8(2)17-10(4-6-15-17)9-3-5-14-11(7-9)16-12(13)18/h3-8H,1-2H3,(H3,13,14,16,18)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The MR competitive binding assay is based on the binding and displacement of a TAMRA-labeled Dexamethasone probe with fluorescence polarization (FP) ...				US Patent US8722709 (2014) BindingDB Entry DOI: 10.7270/Q2NS0SJ4
					More data for this Ligand-Target Pair