BDBM121416 US8722709, 19
SMILES: NC(=O)Nc1cc(ccn1)-c1ccnn1-c1cccc(F)c1
InChI Key: InChIKey=RRHVPTRNEKZKBT-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Mineralocorticoid receptor (Homo sapiens (Human)) | BDBM121416 (US8722709, 19) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 310 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Boehringer Ingelheim International GmbH US Patent | Assay Description The MR competitive binding assay is based on the binding and displacement of a TAMRA-labeled Dexamethasone probe with fluorescence polarization (FP) ... | US Patent US8722709 (2014) BindingDB Entry DOI: 10.7270/Q2NS0SJ4 | |||||||||||
More data for this Ligand-Target Pair |