BDBM12172 (3S,5S)-N-benzyl-5-(pyrrolidin-1-ylcarbonyl)pyrrolidine-3-carboxamide::pyrrolidine-2,4-dicarboxylic acid amide 8h

SMILES: O=C(NCc1ccccc1)[C@@H]1CN[C@@H](C1)C(=O)N1CCCC1

InChI Key: InChIKey=YNOMVALJSRCJTF-GJZGRUSLSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 12172   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM12172 ((3S,5S)-N-benzyl-5-(pyrrolidin-1-ylcarbonyl)pyrrol...) Show SMILES O=C(NCc1ccccc1)[C@@H]1CN[C@@H](C1)C(=O)N1CCCC1 |r| Show InChI InChI=1S/C17H23N3O2/c21-16(19-11-13-6-2-1-3-7-13)14-10-15(18-12-14)17(22)20-8-4-5-9-20/h1-3,6-7,14-15,18H,4-5,8-12H2,(H,19,21)/t14-,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.96E+3	n/a	n/a	n/a	n/a	8.0	37
National Health Research Institutes					Assay Description The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...				Bioorg Med Chem Lett 16: 3268-72 (2006) Article DOI: 10.1016/j.bmcl.2006.03.037 BindingDB Entry DOI: 10.7270/Q22805V8
					More data for this Ligand-Target Pair
Fibroblast Activation Protein (FAP) (Homo sapiens (Human))	BDBM12172 ((3S,5S)-N-benzyl-5-(pyrrolidin-1-ylcarbonyl)pyrrol...) Show SMILES O=C(NCc1ccccc1)[C@@H]1CN[C@@H](C1)C(=O)N1CCCC1 |r| Show InChI InChI=1S/C17H23N3O2/c21-16(19-11-13-6-2-1-3-7-13)14-10-15(18-12-14)17(22)20-8-4-5-9-20/h1-3,6-7,14-15,18H,4-5,8-12H2,(H,19,21)/t14-,15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes					Assay Description The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...				Bioorg Med Chem Lett 16: 3268-72 (2006) Article DOI: 10.1016/j.bmcl.2006.03.037 BindingDB Entry DOI: 10.7270/Q22805V8
					More data for this Ligand-Target Pair
Dipeptidyl peptidase 2 (DPP II) (Homo sapiens (Human))	BDBM12172 ((3S,5S)-N-benzyl-5-(pyrrolidin-1-ylcarbonyl)pyrrol...) Show SMILES O=C(NCc1ccccc1)[C@@H]1CN[C@@H](C1)C(=O)N1CCCC1 |r| Show InChI InChI=1S/C17H23N3O2/c21-16(19-11-13-6-2-1-3-7-13)14-10-15(18-12-14)17(22)20-8-4-5-9-20/h1-3,6-7,14-15,18H,4-5,8-12H2,(H,19,21)/t14-,15-/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes					Assay Description The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...				Bioorg Med Chem Lett 16: 3268-72 (2006) Article DOI: 10.1016/j.bmcl.2006.03.037 BindingDB Entry DOI: 10.7270/Q22805V8
					More data for this Ligand-Target Pair
Dipeptidyl peptidase VIII (Homo sapiens (Human))	BDBM12172 ((3S,5S)-N-benzyl-5-(pyrrolidin-1-ylcarbonyl)pyrrol...) Show SMILES O=C(NCc1ccccc1)[C@@H]1CN[C@@H](C1)C(=O)N1CCCC1 |r| Show InChI InChI=1S/C17H23N3O2/c21-16(19-11-13-6-2-1-3-7-13)14-10-15(18-12-14)17(22)20-8-4-5-9-20/h1-3,6-7,14-15,18H,4-5,8-12H2,(H,19,21)/t14-,15-/m0/s1	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes					Assay Description The enzyme activity resulted in the liberation of free pNA at 405 nm. Reaction progress was monitored using a Molecular Devices SpectraMax Plus micro...				Bioorg Med Chem Lett 16: 3268-72 (2006) Article DOI: 10.1016/j.bmcl.2006.03.037 BindingDB Entry DOI: 10.7270/Q22805V8
					More data for this Ligand-Target Pair