BDBM123022 US8742138, 7

SMILES: OC(=O)CNC(=O)c1c2cc(ccc2c(O)oc1=O)-c1cccc(OC(F)(F)F)c1

InChI Key: InChIKey=FRAQPZUFJJIURS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123022   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Egl nine homolog 1 (Rattus norvegicus (Rat))	BDBM123022 (US8742138, 7) Show SMILES OC(=O)CNC(=O)c1c2cc(ccc2c(O)oc1=O)-c1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C19H12F3NO7/c20-19(21,22)30-11-3-1-2-9(6-11)10-4-5-12-13(7-10)15(18(28)29-17(12)27)16(26)23-8-14(24)25/h1-7,27H,8H2,(H,23,26)(H,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	25
Betta Pharmaceuticals Co., Ltd. US Patent					Assay Description HIF-PHD2 activity was measured using homogeneous TR-FRET technology (see also, US2008/004817; Dao J H et al., Anal Biochem. 2009, 384:213-23). To eac...				US Patent US8742138 (2014) BindingDB Entry DOI: 10.7270/Q23R0RJD
					More data for this Ligand-Target Pair