BDBM123130 1-(2-bromo-4-methylphenyl)-1H-pyrrole-2,5-dione (18)::CID880055

SMILES: Cc1ccc(N2C(=O)C=CC2=O)c(Br)c1

InChI Key: InChIKey=DHXYZCLBPGJGGL-UHFFFAOYSA-N

Data: 1 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123130   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NS3 (Hepatitis C virus)	BDBM123130 (1-(2-bromo-4-methylphenyl)-1H-pyrrole-2,5-dione (1...) Show SMILES Cc1ccc(N2C(=O)C=CC2=O)c(Br)c1 |c:8| Show InChI InChI=1S/C11H8BrNO2/c1-7-2-3-9(8(12)6-7)13-10(14)4-5-11(13)15/h2-6H,1H3	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30E+4	n/a	n/a	n/a	n/a	7.5	23
University of Wisconsin-Milwaukee					Assay Description Binding assays containing 25 mM MOPS pH 7.5, 1.25 mM MgCl2, 20 nM Cy5-dT15, and 200 nM NS3h_1b were incubated 5 min at RT. Following addition of indi...				ACS Chem Biol 9: 2393-2403 (2014) Article DOI: 10.1021/cb500512z BindingDB Entry DOI: 10.7270/Q2G15ZHH
					More data for this Ligand-Target Pair