BDBM123394 US8742106, 6.44

SMILES: Cc1ccc2[C@H](CCc2c1)NC(=O)COc1cc(C)c2c(nn(C)c2n1)C1CC1

InChI Key: InChIKey=LADVEYKZADVBJM-SFHVURJKSA-N

Data: 2 Kd

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 123394   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Homo sapiens (Human))	BDBM123394 (US8742106, 6.44) Show SMILES Cc1ccc2[C@H](CCc2c1)NC(=O)COc1cc(C)c2c(nn(C)c2n1)C1CC1 |r| Show InChI InChI=1S/C23H26N4O2/c1-13-4-8-17-16(10-13)7-9-18(17)24-19(28)12-29-20-11-14(2)21-22(15-5-6-15)26-27(3)23(21)25-20/h4,8,10-11,15,18H,5-7,9,12H2,1-3H3,(H,24,28)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	67	n/a	n/a	n/a	7.5	4
Novartis AG US Patent					Assay Description For crude cell membrane preparations, cells (CHO, Chinese hamster ovary or HEK, human embryonic kidney) expressing human orexin 1 or human orexin 2 r...				US Patent US8742106 (2014) BindingDB Entry DOI: 10.7270/Q22V2DSW
					More data for this Ligand-Target Pair
Orexin receptor type 2 (Homo sapiens (Human))	BDBM123394 (US8742106, 6.44) Show SMILES Cc1ccc2[C@H](CCc2c1)NC(=O)COc1cc(C)c2c(nn(C)c2n1)C1CC1 |r| Show InChI InChI=1S/C23H26N4O2/c1-13-4-8-17-16(10-13)7-9-18(17)24-19(28)12-29-20-11-14(2)21-22(15-5-6-15)26-27(3)23(21)25-20/h4,8,10-11,15,18H,5-7,9,12H2,1-3H3,(H,24,28)/t18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	n/a	28	n/a	n/a	n/a	7.5	4
Novartis AG US Patent					Assay Description For crude cell membrane preparations, cells (CHO, Chinese hamster ovary or HEK, human embryonic kidney) expressing human orexin 1 or human orexin 2 r...				US Patent US8742106 (2014) BindingDB Entry DOI: 10.7270/Q22V2DSW
					More data for this Ligand-Target Pair