BDBM123546 US8748624, 32

SMILES: OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(c(Cl)c1)-c1ccc(Cl)c(c1)C(F)(F)F)C(F)(F)F

InChI Key: InChIKey=UEVAHUUXWZTODT-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123546   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM123546 (US8748624, 32) Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(c(Cl)c1)-c1ccc(Cl)c(c1)C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C30H21Cl2F6N3O3/c31-24-7-2-16(11-23(24)30(36,37)38)21-6-5-20(13-25(21)32)40-14-17-1-4-19(29(33,34)35)12-22(17)18-3-8-26(41-15-18)28(44)39-10-9-27(42)43/h1-8,11-13,15,40H,9-10,14H2,(H,39,44)(H,42,43)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	25.1	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...				US Patent US8748624 (2014) BindingDB Entry DOI: 10.7270/Q29885QP
					More data for this Ligand-Target Pair