BDBM123558 US8748624, 44

SMILES: OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(cc1)-c1ccc(Cl)cc1)C(F)(F)F

InChI Key: InChIKey=HLEWGFZKQGFVQE-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123558   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon receptor (Homo sapiens (Human))	BDBM123558 (US8748624, 44) Show SMILES OC(=O)CCNC(=O)c1ccc(cn1)-c1cc(ccc1CNc1ccc(cc1)-c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C29H23ClF3N3O3/c30-23-8-2-18(3-9-23)19-4-10-24(11-5-19)35-16-20-1-7-22(29(31,32)33)15-25(20)21-6-12-26(36-17-21)28(39)34-14-13-27(37)38/h1-12,15,17,35H,13-14,16H2,(H,34,39)(H,37,38)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	18.4	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Janssen Pharmaceutica NV US Patent					Assay Description The binding assay was performed by a filtration method in a 384 well format. Membranes at a final protein concentration of 6 μg/well were incuba...				US Patent US8748624 (2014) BindingDB Entry DOI: 10.7270/Q29885QP
					More data for this Ligand-Target Pair