BDBM123932 US8754233, 2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-5-fluoro-benzothiazole-6-carboxylic acid methyl ester

SMILES: COC(=O)c1cc2sc(nc2cc1F)-c1c(C)[nH]nc1N

InChI Key: InChIKey=UKMWNGBPFOCSTQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 123932   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase ILK-1 (Homo sapiens (Human))	BDBM123932 (US8754233, 2-(3-Amino-5-methyl-1H-pyrazol-4-yl)-5-...) Show SMILES COC(=O)c1cc2sc(nc2cc1F)-c1c(C)[nH]nc1N Show InChI InChI=1S/C13H11FN4O2S/c1-5-10(11(15)18-17-5)12-16-8-4-7(14)6(13(19)20-2)3-9(8)21-12/h3-4H,1-2H3,(H3,15,17,18)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	40
Dermira (Canada), Inc. US Patent					Assay Description 5 uL of each compound dilution were robotically pipetted to Costar serocluster plates maintaining the same plate layout. All assay mixtures consisted...				US Patent US8754233 (2014) BindingDB Entry DOI: 10.7270/Q23N2231
					More data for this Ligand-Target Pair