BDBM124188 US8748451, 3::US8748451, 7

SMILES: CN1CCc2c(C1)n(CCCCCC(=O)NO)c1ccccc21

InChI Key: InChIKey=IPGBKSUNOKDFQM-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 124188   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM124188 (US8748451, 3 | US8748451, 7) Show SMILES CN1CCc2c(C1)n(CCCCCC(=O)NO)c1ccccc21 Show InChI InChI=1S/C18H25N3O2/c1-20-12-10-15-14-7-4-5-8-16(14)21(17(15)13-20)11-6-2-3-9-18(22)19-23/h4-5,7-8,23H,2-3,6,9-13H2,1H3,(H,19,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	8.0	25
The Board of Trustees of The University of Illinois US Patent					Assay Description HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...				US Patent US8748451 (2014) BindingDB Entry DOI: 10.7270/Q26D5RPK
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM124188 (US8748451, 3 | US8748451, 7) Show SMILES CN1CCc2c(C1)n(CCCCCC(=O)NO)c1ccccc21 Show InChI InChI=1S/C18H25N3O2/c1-20-12-10-15-14-7-4-5-8-16(14)21(17(15)13-20)11-6-2-3-9-18(22)19-23/h4-5,7-8,23H,2-3,6,9-13H2,1H3,(H,19,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	8.0	25
The Board of Trustees of The University of Illinois US Patent					Assay Description HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...				US Patent US8748451 (2014) BindingDB Entry DOI: 10.7270/Q26D5RPK
					More data for this Ligand-Target Pair
Cereblon/Histone deacetylase 6 (Homo sapiens (Human))	BDBM124188 (US8748451, 3 | US8748451, 7) Show SMILES CN1CCc2c(C1)n(CCCCCC(=O)NO)c1ccccc21 Show InChI InChI=1S/C18H25N3O2/c1-20-12-10-15-14-7-4-5-8-16(14)21(17(15)13-20)11-6-2-3-9-18(22)19-23/h4-5,7-8,23H,2-3,6,9-13H2,1H3,(H,19,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	8.0	25
The Board of Trustees of The University of Illinois US Patent					Assay Description HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...				US Patent US8748451 (2014) BindingDB Entry DOI: 10.7270/Q26D5RPK
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM124188 (US8748451, 3 | US8748451, 7) Show SMILES CN1CCc2c(C1)n(CCCCCC(=O)NO)c1ccccc21 Show InChI InChI=1S/C18H25N3O2/c1-20-12-10-15-14-7-4-5-8-16(14)21(17(15)13-20)11-6-2-3-9-18(22)19-23/h4-5,7-8,23H,2-3,6,9-13H2,1H3,(H,19,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	5.18E+3	n/a	n/a	n/a	n/a	8.0	25
The Board of Trustees of The University of Illinois US Patent					Assay Description HDAC assay is performed using fluorescently-labeled acetylated substrate, which comprises an acetylated lysine side chain. After incubation with HDAC...				US Patent US8748451 (2014) BindingDB Entry DOI: 10.7270/Q26D5RPK
					More data for this Ligand-Target Pair