BDBM124211 ({7-[2-({4-[(aminosulfinyl)difluoromethyl]-3-bromophenyl}methyl)-2-(1H-1,2,3-benzotriazol-1-yl)-3-oxo-3-phenylpropyl]-3-bromonaphthalen-2-yl}difluoromethyl)phosphonic acid (10d)

SMILES: NS(=O)C(F)(F)c1ccc(CC(Cc2ccc3cc(Br)c(cc3c2)C(F)(F)P(O)(O)=O)(C(=O)c2ccccc2)n2nnc3ccccc23)cc1Br

InChI Key: InChIKey=CWUUFAFEGKOAFE-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 124211   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein phosphatase non-receptor type 2 (Homo sapiens (Human))	BDBM124211 (({7-[2-({4-[(aminosulfinyl)difluoromethyl]-3-bromo...) Show SMILES NS(=O)C(F)(F)c1ccc(CC(Cc2ccc3cc(Br)c(cc3c2)C(F)(F)P(O)(O)=O)(C(=O)c2ccccc2)n2nnc3ccccc23)cc1Br Show InChI InChI=1S/C34H25Br2F4N4O5PS/c35-27-15-21(11-13-25(27)34(39,40)51(41)49)19-32(31(45)22-6-2-1-3-7-22,44-30-9-5-4-8-29(30)42-43-44)18-20-10-12-23-17-28(36)26(16-24(23)14-20)33(37,38)50(46,47)48/h1-17H,18-19,41H2,(H2,46,47,48)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	192	n/a	n/a	n/a	n/a	n/a	n/a
Zydus Research Centre					Assay Description The in vitro enzyme inhibitory activity was evaluated by using the pNPP assay. Para-nitrophenylphosphate (pNPP) and test compounds were added to assa...				ChemMedChem 6: 1011-6 (2011) Article DOI: 10.1002/cmdc.201100077 BindingDB Entry DOI: 10.7270/Q2XW4HGZ
					More data for this Ligand-Target Pair
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM124211 (({7-[2-({4-[(aminosulfinyl)difluoromethyl]-3-bromo...) Show SMILES NS(=O)C(F)(F)c1ccc(CC(Cc2ccc3cc(Br)c(cc3c2)C(F)(F)P(O)(O)=O)(C(=O)c2ccccc2)n2nnc3ccccc23)cc1Br Show InChI InChI=1S/C34H25Br2F4N4O5PS/c35-27-15-21(11-13-25(27)34(39,40)51(41)49)19-32(31(45)22-6-2-1-3-7-22,44-30-9-5-4-8-29(30)42-43-44)18-20-10-12-23-17-28(36)26(16-24(23)14-20)33(37,38)50(46,47)48/h1-17H,18-19,41H2,(H2,46,47,48)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Zydus Research Centre					Assay Description The in vitro enzyme inhibitory activity was evaluated by using the pNPP assay. Para-nitrophenylphosphate (pNPP) and test compounds were added to assa...				ChemMedChem 6: 1011-6 (2011) Article DOI: 10.1002/cmdc.201100077 BindingDB Entry DOI: 10.7270/Q2XW4HGZ
					More data for this Ligand-Target Pair