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SMILES: Fc1ccc(cc1)C(=O)N1CCC(CC1)C(=O)Nc1ccc(cc1)-c1ccc(NC(=O)C2CCN(CC2)C(=O)c2ccc(F)cc2)cc1

InChI Key: InChIKey=FXZCNYMOIJTMGH-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124239   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein phosphatase non-receptor type 1


(Homo sapiens (Human))		BDBM124239
PNG
(N,N'-([1,1'-biphenyl]-4,4'-diyl)bis(1-...)
Show SMILES Fc1ccc(cc1)C(=O)N1CCC(CC1)C(=O)Nc1ccc(cc1)-c1ccc(NC(=O)C2CCN(CC2)C(=O)c2ccc(F)cc2)cc1
Show InChI InChI=1S/C38H36F2N4O4/c39-31-9-1-29(2-10-31)37(47)43-21-17-27(18-22-43)35(45)41-33-13-5-25(6-14-33)26-7-15-34(16-8-26)42-36(46)28-19-23-44(24-20-28)38(48)30-3-11-32(40)12-4-30/h1-16,27-28H,17-24H2,(H,41,45)(H,42,46)
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Article
PubMed
n/an/a 5.04E+3n/an/an/an/an/an/a



Jiangnan University



Assay Description
IC50 values were determined by pNPP assay.

Bioorg Med Chem Lett 24: 1889-94 (2014)


Article DOI: 10.1016/j.bmcl.2014.03.015
BindingDB Entry DOI: 10.7270/Q2PC3122
More data for this
Ligand-Target Pair