BDBM124812 US8759386, 9

SMILES: COc1cccc2cc(oc12)C(=O)Nc1ccc(Cn2nc(C)c(CC(O)=O)c2C)cc1

InChI Key: InChIKey=CGSRGTYHERKVAK-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124812   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM124812 (US8759386, 9) Show SMILES COc1cccc2cc(oc12)C(=O)Nc1ccc(Cn2nc(C)c(CC(O)=O)c2C)cc1 Show InChI InChI=1S/C24H23N3O5/c1-14-19(12-22(28)29)15(2)27(26-14)13-16-7-9-18(10-8-16)25-24(30)21-11-17-5-4-6-20(31-3)23(17)32-21/h4-11H,12-13H2,1-3H3,(H,25,30)(H,28,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.20	-12.2	n/a	n/a	n/a	n/a	n/a	7.4	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8759386 (2014) BindingDB Entry DOI: 10.7270/Q2S46QM5
					More data for this Ligand-Target Pair