BDBM124841 US8759386, 38

SMILES: CCc1c(oc2c(Cl)cccc12)C(=O)Nc1ccc(Cn2nc(C)c(CC(O)=O)c2C)c(F)c1

InChI Key: InChIKey=FDUBUKGQKDTZRI-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124841   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM124841 (US8759386, 38) Show SMILES CCc1c(oc2c(Cl)cccc12)C(=O)Nc1ccc(Cn2nc(C)c(CC(O)=O)c2C)c(F)c1 Show InChI InChI=1S/C25H23ClFN3O4/c1-4-17-18-6-5-7-20(26)23(18)34-24(17)25(33)28-16-9-8-15(21(27)10-16)12-30-14(3)19(11-22(31)32)13(2)29-30/h5-10H,4,11-12H2,1-3H3,(H,28,33)(H,31,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.600	-12.6	n/a	n/a	n/a	n/a	n/a	7.4	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8759386 (2014) BindingDB Entry DOI: 10.7270/Q2S46QM5
					More data for this Ligand-Target Pair