BDBM124842 US8759386, 39

SMILES: Cc1nn(Cc2ccc(NC(=O)c3cc4ccc(Cl)cc4o3)cc2F)c(C)c1CC(O)=O

InChI Key: InChIKey=RFUQJXMXSQQWEP-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124842   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin D2 receptor 2 (Homo sapiens (Human))	BDBM124842 (US8759386, 39) Show SMILES Cc1nn(Cc2ccc(NC(=O)c3cc4ccc(Cl)cc4o3)cc2F)c(C)c1CC(O)=O Show InChI InChI=1S/C23H19ClFN3O4/c1-12-18(10-22(29)30)13(2)28(27-12)11-15-4-6-17(9-19(15)25)26-23(31)21-7-14-3-5-16(24)8-20(14)32-21/h3-9H,10-11H2,1-2H3,(H,26,31)(H,29,30)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.400	-12.8	n/a	n/a	n/a	n/a	n/a	7.4	25
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8759386 (2014) BindingDB Entry DOI: 10.7270/Q2S46QM5
					More data for this Ligand-Target Pair