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SMILES: Cc1[nH]nc2ccc(cc12)C1C2C(=O)OCC2=NC(=C1[N+]#[C-])c1ccc(F)cc1F

InChI Key: InChIKey=SOLZLGSOKZXYLX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 124893   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor


(Homo sapiens (Human))		BDBM124893
PNG
(US8759341, 31)
Show SMILES Cc1[nH]nc2ccc(cc12)C1C2C(=O)OCC2=NC(=C1[N+]#[C-])c1ccc(F)cc1F |c:19,21|
Show InChI InChI=1S/C22H14F2N4O2/c1-10-14-7-11(3-6-16(14)28-27-10)18-19-17(9-30-22(19)29)26-20(21(18)25-2)13-5-4-12(23)8-15(13)24/h3-8,18-19H,9H2,1H3,(H,27,28)
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KEGG

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Similars
US Patent
n/an/a 2n/an/an/an/a7.522



Bayer Intellectual Property GmbH

US Patent


Assay Description
For the assay, 50 mL of a 100-fold concentrated solution of the test compound in DMSO is pipetted into a black low-volume 384-well microtiter plate (...

US Patent US8759341 (2014)


BindingDB Entry DOI: 10.7270/Q2HQ3XMW
More data for this
Ligand-Target Pair