BDBM125002 US8772510, 21

SMILES: Cn1ncc(C(=O)N2CCC2)c1C(=O)NCCc1noc(n1)-c1ccccc1

InChI Key: InChIKey=ZUQSFCBMKAAWMP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125002   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM125002 (US8772510, 21) Show SMILES Cn1ncc(C(=O)N2CCC2)c1C(=O)NCCc1noc(n1)-c1ccccc1 Show InChI InChI=1S/C19H20N6O3/c1-24-16(14(12-21-24)19(27)25-10-5-11-25)17(26)20-9-8-15-22-18(28-23-15)13-6-3-2-4-7-13/h2-4,6-7,12H,5,8-11H2,1H3,(H,20,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	202	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc. US Patent					Assay Description PDE10 activity of the compounds of the present invention was determined using a Scintillation Proximity Assay (SPA)-based method similar to the one p...				US Patent US8772510 (2014) BindingDB Entry DOI: 10.7270/Q2MG7N67
					More data for this Ligand-Target Pair