BDBM125060 US8765733, 45

SMILES: CC(C(=O)NCc1ccc(nc1N1CCCC1)C(F)(F)F)c1ccc(CNS(C)(=O)=O)c(Cl)c1

InChI Key: InChIKey=LIVGIEWMGKYQDQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125060   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM125060 (US8765733, 45) Show SMILES CC(C(=O)NCc1ccc(nc1N1CCCC1)C(F)(F)F)c1ccc(CNS(C)(=O)=O)c(Cl)c1 Show InChI InChI=1S/C22H26ClF3N4O3S/c1-14(15-5-6-16(18(23)11-15)13-28-34(2,32)33)21(31)27-12-17-7-8-19(22(24,25)26)29-20(17)30-9-3-4-10-30/h5-8,11,14,28H,3-4,9-10,12-13H2,1-2H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The FLIPR protocol consists of 2 substance additions. First the compounds to be tested (10 μM) are pipetted onto the cells and the Ca2+ influx i...				US Patent US8765733 (2014) BindingDB Entry DOI: 10.7270/Q2BZ64QQ
					More data for this Ligand-Target Pair