BDBM125064 US8765733, 51

SMILES: CC(C(=O)NCc1ccc(nc1N1CCCC1)C(F)(F)F)c1ccc(CNS(C)(=O)=O)c(C)c1

InChI Key: InChIKey=HRJSGGWXLOJFAA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125064   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Homo sapiens (Human))	BDBM125064 (US8765733, 51) Show SMILES CC(C(=O)NCc1ccc(nc1N1CCCC1)C(F)(F)F)c1ccc(CNS(C)(=O)=O)c(C)c1 Show InChI InChI=1S/C23H29F3N4O3S/c1-15-12-17(6-7-18(15)14-28-34(3,32)33)16(2)22(31)27-13-19-8-9-20(23(24,25)26)29-21(19)30-10-4-5-11-30/h6-9,12,16,28H,4-5,10-11,13-14H2,1-3H3,(H,27,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Gruenenthal GmbH US Patent					Assay Description The FLIPR protocol consists of 2 substance additions. First the compounds to be tested (10 μM) are pipetted onto the cells and the Ca2+ influx i...				US Patent US8765733 (2014) BindingDB Entry DOI: 10.7270/Q2BZ64QQ
					More data for this Ligand-Target Pair