BDBM12513 (2S)-2-[(3S)-3-[(6-chloronaphthalene-2-)sulfonamido]-2-oxopyrrolidin-1-yl]-N-ethyl-N-(pyridin-4-ylmethyl)propanamide::P4 alanylamide pyrrolidin-2-one 24

SMILES: CCN(Cc1ccncc1)C(=O)[C@H](C)N1CC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O

InChI Key: InChIKey=XHNRETTXQLOZNQ-SBUREZEXSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 12513   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM12513 ((2S)-2-[(3S)-3-[(6-chloronaphthalene-2-)sulfonamid...) Show SMILES CCN(Cc1ccncc1)C(=O)[C@H](C)N1CC[C@H](NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O |r| Show InChI InChI=1S/C25H27ClN4O4S/c1-3-29(16-18-8-11-27-12-9-18)24(31)17(2)30-13-10-23(25(30)32)28-35(33,34)22-7-5-19-14-21(26)6-4-20(19)15-22/h4-9,11-12,14-15,17,23,28H,3,10,13,16H2,1-2H3/t17-,23-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	27	-10.3	n/a	n/a	n/a	n/a	n/a	7.8	25
GlaxoSmithKline					Assay Description The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrate. The hydrolysis rates of chromogenic substrate...				Bioorg Med Chem Lett 16: 5953-7 (2006) Article DOI: 10.1016/j.bmcl.2006.09.001 BindingDB Entry DOI: 10.7270/Q2CF9NB8
					More data for this Ligand-Target Pair