BDBM125536 US8772316, 19

SMILES: CCc1[nH]c(=O)c(Cc2ccc3ccccc3c2)c2cc(OC)c(OC)cc12

InChI Key: InChIKey=WDDKLHMVLDAROO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125536   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM125536 (US8772316, 19) Show SMILES CCc1[nH]c(=O)c(Cc2ccc3ccccc3c2)c2cc(OC)c(OC)cc12 Show InChI InChI=1S/C24H23NO3/c1-4-21-19-14-23(28-3)22(27-2)13-18(19)20(24(26)25-21)12-15-9-10-16-7-5-6-8-17(16)11-15/h5-11,13-14H,4,12H2,1-3H3,(H,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.4	n/a
Allergan, Inc.; Exonhit Therapeutics SA US Patent					Assay Description The PDE assay is based on the homogenous time-resolved fluorescence resonance energy transfer (TR-FRET) technology (LANCE from Perkin Elmer). This co...				US Patent US8772316 (2014) BindingDB Entry DOI: 10.7270/Q2Q81BR8
					More data for this Ligand-Target Pair