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SMILES: CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2cccc(c2)S(=O)(=O)Nc2ccc(cc2)N2CCCCC2)CC1

InChI Key: InChIKey=WSLPNSLOAVFHRC-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 125980   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
TGF-beta receptor type-1


(Homo sapiens (Human))		BDBM125980
PNG
(US8772297, Y224)
Show SMILES CC(C)(C)OC(=O)N1CCC(CNS(=O)(=O)c2cccc(c2)S(=O)(=O)Nc2ccc(cc2)N2CCCCC2)CC1
Show InChI InChI=1S/C28H40N4O6S2/c1-28(2,3)38-27(33)32-18-14-22(15-19-32)21-29-39(34,35)25-8-7-9-26(20-25)40(36,37)30-23-10-12-24(13-11-23)31-16-5-4-6-17-31/h7-13,20,22,29-30H,4-6,14-19,21H2,1-3H3
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MMDB

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PC sid
UniChem

Similars
US Patent
n/an/a 2.40E+3n/an/an/an/an/an/a



Kyoto University

US Patent


Assay Description
The biological activity of a compound was determined by measuring the activation of Smad3/Smad4 complex which is a transcription factor showing activ...

US Patent US8772297 (2014)


BindingDB Entry DOI: 10.7270/Q2XS5T2N
More data for this
Ligand-Target Pair