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SMILES: CN1C(=O)NC(=O)C11Cc2cc3ccc(CN4C(=O)C(C)(C)Nc5ccccc45)nc3cc2C1

InChI Key: InChIKey=GTNOYYBFJLEGKA-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 126182   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calcitonin gene-related peptide 1


(Homo sapiens (Human))		BDBM126182
PNG
(US8778957, 8)
Show SMILES CN1C(=O)NC(=O)C11Cc2cc3ccc(CN4C(=O)C(C)(C)Nc5ccccc45)nc3cc2C1
Show InChI InChI=1S/C26H25N5O3/c1-25(2)23(33)31(21-7-5-4-6-19(21)29-25)14-18-9-8-15-10-16-12-26(13-17(16)11-20(15)27-18)22(32)28-24(34)30(26)3/h4-11,29H,12-14H2,1-3H3,(H,28,32,34)
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Similars
US Patent
 35 -10.2n/an/an/an/an/a7.425



Merck Sharp & Dohme Corp.

US Patent


Assay Description
Cells expressing recombinant human CL receptor/RAMP1 were washed with PBS and harvested in harvest buffer containing 50 mM HEPES, 1 mM EDTA and Compl...

US Patent US8778957 (2014)


BindingDB Entry DOI: 10.7270/Q29022G8
More data for this
Ligand-Target Pair