BDBM126600 US8772283, 44

SMILES:

InChI Key: InChIKey=XHQAOCRKKBUCMA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 126600   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase AKT2 (Homo sapiens (Human))	BDBM126600 (US8772283, 44) Show SMILES Show InChI InChI=1S/C28H27N3O3/c1-27(33)15-28(29,16-27)21-10-8-19(9-11-21)24-25(20-5-3-2-4-6-20)31-17-34-23-12-7-18(14-32)13-22(23)26(31)30-24/h2-13,32-33H,14-17,29H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.550	n/a	n/a	n/a	n/a	7.5	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...				US Patent US8772283 (2014) BindingDB Entry DOI: 10.7270/Q21J98F0
					More data for this Ligand-Target Pair
RAC-alpha serine/threonine-protein kinase (Homo sapiens (Human))	BDBM126600 (US8772283, 44) Show SMILES Show InChI InChI=1S/C28H27N3O3/c1-27(33)15-28(29,16-27)21-10-8-19(9-11-21)24-25(20-5-3-2-4-6-20)31-17-34-23-12-7-18(14-32)13-22(23)26(31)30-24/h2-13,32-33H,14-17,29H2,1H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	7.5	n/a
Taiho Pharmaceutical Co., Ltd. US Patent					Assay Description Preparation of AKT1 and AKT2 and measurement of in vitro inhibitory activity of the above-mentioned compounds against AKT1 and AKT2 kinase activity w...				US Patent US8772283 (2014) BindingDB Entry DOI: 10.7270/Q21J98F0
					More data for this Ligand-Target Pair