BDBM127154 US8791272, 2.8

SMILES: Cc1nn(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2)c(c1CC(O)=O)-c1ccccc1

InChI Key: InChIKey=SMSIQMOUVYCIHV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 127154   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM127154 (US8791272, 2.8) Show SMILES Cc1nn(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2)c(c1CC(O)=O)-c1ccccc1 Show InChI InChI=1S/C30H25N3O3/c1-20-27(18-28(34)35)29(23-8-3-2-4-9-23)33(32-20)19-21-11-15-26(16-12-21)31-30(36)25-14-13-22-7-5-6-10-24(22)17-25/h2-17H,18-19H2,1H3,(H,31,36)(H,34,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	1.30	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair