BDBM127156 US8791272, 2.10

SMILES: Cc1nn(Cc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2)c(c1CC(O)=O)-c1ccccc1

InChI Key: InChIKey=JEWYMLBXYHJCJV-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 127156   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
G protein-coupled receptor 44 (Homo sapiens (Human))	BDBM127156 (US8791272, 2.10) Show SMILES Cc1nn(Cc2ccc(NC(=O)c3ccc(Cl)c(Cl)c3)cc2)c(c1CC(O)=O)-c1ccccc1 Show InChI InChI=1S/C26H21Cl2N3O3/c1-16-21(14-24(32)33)25(18-5-3-2-4-6-18)31(30-16)15-17-7-10-20(11-8-17)29-26(34)19-9-12-22(27)23(28)13-19/h2-13H,14-15H2,1H3,(H,29,34)(H,32,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.800	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...				US Patent US8791272 (2014) BindingDB Entry DOI: 10.7270/Q2GH9GNV
					More data for this Ligand-Target Pair