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SMILES: Cc1nn(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2F)c(C)c1CC(O)=O

InChI Key: InChIKey=GTPPEAKYHPGJCZ-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 127224   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prostaglandin D2 receptor 2


(Homo sapiens (Human))		BDBM127224
PNG
(US8791272, 7.20)
Show SMILES Cc1nn(Cc2ccc(NC(=O)c3ccc4ccccc4c3)cc2F)c(C)c1CC(O)=O
Show InChI InChI=1S/C25H22FN3O3/c1-15-22(13-24(30)31)16(2)29(28-15)14-20-9-10-21(12-23(20)26)27-25(32)19-8-7-17-5-3-4-6-18(17)11-19/h3-12H,13-14H2,1-2H3,(H,27,32)(H,30,31)
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Similars
US Patent
 2.20n/an/an/an/an/an/a7.4n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The CRTH2 receptor binding assay is performed in a scintillation proximity assay (SPA) format with the radioligand [3H]-PGD2 (Perkin Elmer, NET616000...

US Patent US8791272 (2014)


BindingDB Entry DOI: 10.7270/Q2GH9GNV
More data for this
Ligand-Target Pair