BDBM127336 US8791257, 187

SMILES: CC(C)(C)C(OC(N)=O)C1CCN(C1)C(=O)c1cc(-c2ccncc2)n2ncnc(N)c12

InChI Key: InChIKey=RZJHGWHDPRIOAV-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 127336   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Casein kinase II alpha' (Homo sapiens (Human))	BDBM127336 (US8791257, 187) Show SMILES CC(C)(C)C(OC(N)=O)C1CCN(C1)C(=O)c1cc(-c2ccncc2)n2ncnc(N)c12 Show InChI InChI=1S/C22H27N7O3/c1-22(2,3)18(32-21(24)31)14-6-9-28(11-14)20(30)15-10-16(13-4-7-25-8-5-13)29-17(15)19(23)26-12-27-29/h4-5,7-8,10,12,14,18H,6,9,11H2,1-3H3,(H2,24,31)(H2,23,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	560	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8791257 (2014) BindingDB Entry DOI: 10.7270/Q2736PMF
					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM127336 (US8791257, 187) Show SMILES CC(C)(C)C(OC(N)=O)C1CCN(C1)C(=O)c1cc(-c2ccncc2)n2ncnc(N)c12 Show InChI InChI=1S/C22H27N7O3/c1-22(2,3)18(32-21(24)31)14-6-9-28(11-14)20(30)15-10-16(13-4-7-25-8-5-13)29-17(15)19(23)26-12-27-29/h4-5,7-8,10,12,14,18H,6,9,11H2,1-3H3,(H2,24,31)(H2,23,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	7.4	30
Bristol-Myers Squibb Company US Patent					Assay Description The effectiveness of compounds of the present invention as inhibitors of protein kinases can be readily tested by assays known to those skilled in th...				US Patent US8791257 (2014) BindingDB Entry DOI: 10.7270/Q2736PMF
					More data for this Ligand-Target Pair