BDBM127612 US8791118, 175

SMILES: OCc1cccc(c1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1

InChI Key: InChIKey=FNRZJZHDLZAOOT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 127612   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase 1 (Homo sapiens (Human))	BDBM127612 (US8791118, 175) Show SMILES OCc1cccc(c1)-c1cnc2ccc(NC(=O)NCCCCc3ccccc3)nc2n1 Show InChI InChI=1S/C25H25N5O2/c31-17-19-10-6-11-20(15-19)22-16-27-21-12-13-23(29-24(21)28-22)30-25(32)26-14-5-4-9-18-7-2-1-3-8-18/h1-3,6-8,10-13,15-16,31H,4-5,9,14,17H2,(H2,26,28,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	6	n/a	n/a	n/a	n/a	7.5	n/a
Aeterna Zentaris GmbH US Patent					Assay Description The inhibitory effect of the compounds according to the invention was tested on various serine/threonine, tyrosine and lipid kinases in enzymatic ass...				US Patent US8791118 (2014) BindingDB Entry DOI: 10.7270/Q2TT4PNN
					More data for this Ligand-Target Pair